威爾斯啟發了黑色電影風格，又以這個類型風格來處理本片。平靜小城受人尊敬的教授原來是納粹餘孽，聯邦密探微服偵查，引發出連場殺戮。威爾斯飾演教授，與康城影帝愛德華．羅便臣飾演的聯邦密探，大鬥演技，成為一時佳話。殺人毒計更為影片帶來奧斯卡最佳原著劇本和***影展最佳電影金獅獎提名，又是他最賣座的電影。 　　Welles, who had been an original inspiration of film noir, skillfully incorporated the noir element into this thriller of deceit and murder. Welles plays a well-respected small town professor who was actually a Nazi fugitive. The i...